Roche and its subsidiary TIB Molbiol have developed a series of tests for the detection of the monkeypox virus, the Switzerland-based pharmaceutical company announced.
The monkeypox virus is a close relative of the smallpox virus, belonging to orthpoxviridae in the poxviridae family.
The modular virus detection tool, called LightMix, includes three orthpoxvirus detection kits with different functions, Roche said in a statement. The first kit detects orthpoxvirus; The second kit tests only for monkeypox virus (west and Central African branches); The third kit contains the main functions of the first two kits, showing specific information on the presence of the monkeypox virus (west and Central African branches) as well as the detection of orpoxvirus.
Thomas Schinek, a Roche executive, said the new test could detect monkeypox and help track its spread. Such diagnostic tools are critical for addressing and ultimately managing emerging public health challenges, as they advance responses such as tracking efforts and treatment strategies.
The monkeypox virus was first identified in 1958 in a group of monkeys used for research when the animals developed a "pox-like" infection, hence the name. Since May, several non-endemic countries have reported human cases of the monkeypox virus, including the United Kingdom, the United States, Portugal, Spain, and Italy.
Affected by the ever-changing international situation, the supply and prices of international bulk water reducer,water reducing agent ,concrete admixtures are still very uncertain.
The application of various concrete admixtures can not only improve the performance of concrete, but also promote the development of new concrete technologies, promote the application of industrial by-products in cementitious material systems, and also help save resources and protect the environment. , has gradually become an essential material for high-quality concrete. Among them, the water reducing agent is a kind of concrete, and the water reducing agent is a concrete admixture that can reduce the mixing water consumption under the condition that the concrete slump is basically unchanged. Most of them are anionic surfactants, such as lignosulfonate, naphthalene sulfonate formaldehyde polymer, etc. When we add the concrete mixture, it has a dispersing effect on the cement particles, which can improve its workability, reduce the unit water consumption, and improve the fluidity of the concrete mixture; or reduce the unit cement consumption, effectively saving cement.
The specific operation method of the water reducing agent formula for concrete:
1. Maleic anhydride is prepared into a 5-7% solution according to the required amount and recorded as the head material.
2. The initiator is prepared into a 5-10% solution for later use.
3. Add the required amount of APEG or TPEG, heat to liquefy it, and then add the headstock.
4. Nitrogen replacement;
5. When the temperature rises to 75-85°C, the initiator is added dropwise, and the dropwise addition is completed at 80°C for 1.5-2 hours.
6. After the dropwise addition of the initiator is completed, keep the temperature at 80-90° C. for 4-4.5 hours to complete the reaction and cool down.
7. When the temperature drops to 40-50℃, add 50% KOH solution to neutralize to PH: 7-8.
8. After measuring the solid content, add the measured soft water according to the required solid content.
9. After the solid content is determined to be qualified, discharge the material.
After the above experiments, we can get the basic formula of water reducer for concrete:
Concrete water reducer formula 1:
Hydroxyethyl acrylate: 25g, acrylamide: 5g, allyl polyoxyethylene ether: 175g, sodium persulfate: 10g, neutralized by sodium hydroxide.
Concrete water reducer formula 2:
Allyl polyoxyethylene glycol ether: 40 g, acrylic monomer: 30 g, 10% ammonium persulfate aqueous solution 40 g, neutralized with triethanolamine.
Concrete water reducer formula 3:
Allyl polyoxyethylene glycol ether: 100 g, methacrylic acid: 70 g, acrylic acid: 20 g, 10% aqueous ammonium persulfate solution: 50 g, neutralized with sodium hydroxide.
Concrete water reducer formula 4:
Methacrylic acid: 25g:, allyl polyoxyethylene ether: 175g, sodium persulfate: 10g. , neutralized with sodium hydroxide.
Concrete water reducer formula 5:
TPEG: 180 g, hydrogen peroxide: 0.63 g, thioglycolic acid: 0.56 g, ascorbic acid: 0.3 g, acrylic acid: 182.3 g, neutralized with sodium hydroxide.
Concrete water reducer formula 6:
APEG: 180 g, hydrogen peroxide: 10 g, thioglycolic acid: 2.07 g, itaconic acid: 10 g, methacrylic acid: 21.23 g, neutralized with sodium hydroxide.
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