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Colloidal Gold toxic gas detection

wallpapers News 2021-12-30
Researchers have developed a simple, inexpensive method for detecting hydrogen sulfide in the field
Based on the anti-aggregation effect of gold nanoparticles (AuNPs), 2S are present in the air. Dissolved H
The 2S enter the weakly alkaline buffer solution, resulting in the formation of HS-, which stabilizes AuNPs and ensures that they remain red, allowing the naked eye to detect toxicity levels of H2S.
Colloidal Gold biosensor based on gold nanoparticles
Colloidal Gold nanoparticles are introduced into biosensors to improve their stability, sensitivity, and selectivity nanoparticle properties such as small size, high surface-to-volume ratio, and high surface energy that allows the fixation of a wide range of biomolecules. Gold nanoparticles, in particular, can also act as "electron filaments" to transport electrons, and their magnifying effect on electromagnetic light allows them to act as signal amplifiers. Biosensors based on gold nanoparticles mainly include optical biosensors and electrochemical biosensors.
Colloidal Gold optical biosensor
Colloidal Gold nanoparticles (AU-NP) glutathione (GSH) biosensor.AuNPs partially disintegrate NPS by functionalizing the chemical groups bound to glutathione, thereby changing color. The exact content of glutathione can be determined by a calibration curve in the UV-vis spectrum.
Gold nanoparticles can improve the sensitivity of optical sensors by responding to local refractive index changes. Surface plasmon resonance is an interaction between light waves and conductive electrons in a metal, where the Angle of incident light changes when other substances are bound to the metal surface. Since gold is very sensitive to the dielectric constant of its surroundings, the binding of analytes will significantly change the SPR of gold nanoparticles, thus allowing for more sensitive detection. Gold nanoparticles can also amplify SPR signals As plasma waves pass through gold nanoparticles, the charge density in the waves interacts with the electrons in gold, producing a higher energy response, that is, the electron coupling because the analyte and biological receptors are now binding to gold, it increases the apparent mass of the analyte, Thus amplifiers the signal these properties have been used to construct DNA sensors that are 1000 times more sensitive than non-Au-NP. Humidity sensors are also constructed by varying the intermolecular atomic spacing, which also leads to changes in the LSPR of Au NP.
Colloidal Gold electrochemical biosensor
Electrochemical sensors convert bio information into electrical signals that can be detected.Au NP's electrical conductivity and biocompatibility enable it to act as an "electron filament" that transfers electrons between the electrode and the active site of the enzyme. This can be done in two ways: by attaching Au NP to an enzyme or electrode.GNP - glucose oxidase monolayer electrode was constructed by these two methods.Au NP makes the localization of the enzyme freer, thus making the detection more sensitive and stable.Au NP also acts as a stationary platform for enzyme.Most biomolecules denature or inactivate when interacting with electrodes Au's biocompatibility and high surface energy enable it to bind to a large number of proteins without changing its activity, making it a more sensitive sensor. In addition, Au NP can catalyze biological reactions. Gold nanoparticles exhibit catalytic activity for styrene oxidation at 2 nm.
Colloidal Gold immunobiosensor
Gold nanoparticles coated with peptides and glycans are used in immunoassay methods. The possibility of using glycan particles in ELISA was unexpected, but the method appears to have a high sensitivity and thus offers potential for developing specific assays for the diagnostic identification of antibodies in patient serum 
 

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